Human biology can be complex, in part due to the function and interplay of the body’s approximately 37 trillion cells, which are organized into tissues, organs, and systems. However, recent advances ...

Bolt is a high-level, embeddable language with a rich type system. It aims to combine the best parts of other scripting environments like Lua or Python while integrating typing directly into the ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Allosteric compounds offer an alternative mode of inhibition to orthosteric compounds ...

In this manuscript, we address an essential question in developmental and evolutionary biology: How have changes in gene regulatory networks contributed to the invertebrate-to-vertebrate transition?

De novo design seeks to generate molecules with required property profiles by virtual design-make-test cycles. With the emergence of deep learning and neural generative models in many application ...

Cell classifier circuits are synthetic biological circuits capable of distinguishing between different cell states depending on specific cellular markers and engendering a state-specific response. An ...